Gene test could personalize Anti-Nausea treatment for breast cancer chemo
NCT ID NCT07455955
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study is testing whether a genetic test can help doctors choose the best anti-nausea drugs for Chinese women with early breast cancer undergoing chemotherapy. About 200 participants will either receive standard anti-nausea medication or a personalized regimen based on their genetic profile. The goal is to see if the personalized approach reduces vomiting and nausea and improves quality of life.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Standard antiemetic regimen (aprepitant, ondansetron, dexamethasone) with or without olanzapine
What this could lead to
If successful, this could lead to a personalized approach to prevent chemotherapy-induced nausea and vomiting, improving comfort and quality of life for breast cancer patients.
What could go wrong
This is a small, early-phase study (Phase 2) with only 200 Chinese breast cancer patients, so results may not apply to other groups. The genetic test may not reliably predict which antiemetic works best, and olanzapine can cause side effects like drowsiness.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Department of Clinical Oncology, Prince of Wales Hospital
RECRUITINGHong Kong, Hong Kong
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••