Lab-Grown tumor avatars could pick the right cancer drug for each patient

NCT ID NCT06077591

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a personalized approach for patients with advanced liver or colorectal cancers that no longer respond to standard treatments. Doctors take a small sample of the tumor, grow it in the lab as 3D 'organoids', and test different drugs on them to see which works best. The goal is to see if this method can improve tumor shrinkage and survival compared to usual care.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Patient-derived tumor organoid (PDO) drug screening and next-generation sequencing (NGS) to guide treatment selection

What this could lead to

If successful, this approach could provide a new way to select effective treatments for patients with advanced cancers who have run out of standard options.

What could go wrong

This is a small, early-phase study with only 40 participants. The organoid culture may fail for some patients, and the drug screen results may not always match real-world response.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

colorectal cancer colorectal neoplasm hepatocellular carcinoma neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Endoscopy Centre, Prince of Wales Hospital

    RECRUITING

    Hong Kong, N.T., 123, Hong Kong

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••