Blood test may reveal if radiotherapy is working for liver cancer

NCT ID NCT06885879

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at how pieces of tumor DNA circulating in the blood change in 15 liver cancer patients receiving a precise type of radiotherapy called SBRT. Researchers will take blood samples before, during, and up to 6 months after treatment to see if these DNA changes can help tell if the cancer is responding. The goal is to find a better way to monitor treatment than relying on standard scans, which can be misleading for months after radiotherapy.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Stereotactic Body Radiation Therapy (SBRT)

What this could lead to

If successful, this could lead to a simple blood test to monitor how well radiotherapy is working for liver cancer patients, replacing unclear imaging results.

What could go wrong

This is a very small, early study with only 15 participants. It is designed to observe changes, not to prove a treatment works, so results may not apply broadly.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

hepatocellular carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Department of Clinical Oncology, Prince of Wales Hospital

    RECRUITING

    Hong Kong, Hong Kong

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••