New dual immunotherapy aims to stop liver cancer recurrence after surgery

NCT ID NCT07658105

First seen Jun 24, 2026 · Last updated Jun 24, 2026

Summary

This phase 2 trial tests whether eparlitozoviril, a dual immunotherapy drug, can prevent liver cancer from returning after surgery in patients with microvascular invasion (MVI), a high-risk feature. About 60 participants will receive the drug or active surveillance. The main goal is to see how many remain cancer-free after one year.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Tianjin Medical University Cancer Institute and Hospital

    Tianjin, Tianjin Municipality, 300060, China

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

eparlitozoviril (a dual immunotherapy drug targeting PD-1 and CTLA-4)

What this could lead to

If successful, this could provide a new option to lower the chance of liver cancer returning after surgery for patients with microvascular invasion.

What could go wrong

This is a small, early-phase study (60 people) at one center, so results may not apply broadly. Immunotherapy can cause serious side effects like immune system overactivation.

Conditions

The condition(s) this trial relates to.

Carcinoma, Hepatocellular

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.