Shorter infusion may be just as good for preventing repeat variceal bleeding

NCT ID NCT03624517

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at whether giving the drug octreotide for 24 hours instead of the usual 72 hours could prevent early rebleeding from esophageal varices in people with cirrhosis. The trial included 34 adults with active bleeding from varices who underwent endoscopic banding. The goal was to see if the shorter infusion was safe and effective, but the study was stopped early, so the findings are not conclusive.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

octreotide

What this could lead to

If successful, this could show that a shorter 24-hour octreotide infusion is just as safe and effective as the standard 72-hour regimen, potentially reducing hospital stay and treatment burden.

What could go wrong

The trial was terminated early with only 34 participants, so results are limited and may not be reliable. It is unclear if the shorter infusion truly prevents rebleeding as well as the longer one.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for LIVER CIRRHOSES are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

cirrhosis of liver esophageal varices Gastrointestinal Hemorrhage

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Brooke Army Medical Center

    Houston, Texas, 78234, United States

  • Medical University of South Carolina

    Charleston, South Carolina, 29425, United States

  • Oregon Health & Science University

    Portland, Oregon, 97239, United States

  • Texas Tech University Health Sciences Center

    El Paso, Texas, 79905, United States

  • The Ohio state University

    Columbus, Ohio, 43210, United States

  • The University of Texas at Austin

    Austin, Texas, 78712, United States

  • University of Florida Health

    Jacksonville, Florida, 32209, United States

  • University of Illinois at Chicago

    Chicago, Illinois, 60607, United States