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Aortic repair breakthrough: which blood flow restore method works best?

NCT ID NCT07697820

Disease control Sponsor: Assiut University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 13, 2026 · Last updated Jul 14, 2026 · Updated 1 time

Summary

This study looks at different methods to restore blood flow to the left subclavian artery when it must be covered during aortic repair. Covering this artery can raise the risk of stroke and arm problems. The trial compares surgical bypass with newer endovascular techniques to see which is safer and more effective. It includes adults with aortic aneurysms or dissections who need this type of repair.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Carotid-subclavian bypass (surgical procedure)
What this could lead to
If successful, this study could help doctors choose the safest revascularization method for patients needing aortic repair, reducing the risk of stroke and arm complications.
What could go wrong
This is a small, single-center study with only 50 participants, so results may not apply to all patients. Surgical and endovascular techniques each carry their own risks, such as infection or endoleaks.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 50 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Oct 2026

An estimate. Start dates often move.

Expected to finish

Dec 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Patients ≥18 years Undergoing TEVAR with proximal landing in zone 2 whether acute or chronic type B aortic dissection (TBAD), thoraco-abdominal aortic aneurysm (TAAA), penetrating aortic ulcer (PAU) or intramural hematoma (IMH). • Treatment with one of the following: * Single-branched stent grafts * In-situ fenestration (e.g. ISLF ± stent) * Chimney/periscope graft techniques * Physician-modified endografts (PMEGs) * Carotid-subclavian bypass, carotid-axillary bypass, or subclavian transposition Exclusion Criteria: * • Non revascularized left subclavian artery. * Zone 0 or 1 procedures * Multi-vessel arch debranching * Blunt traumatic aortic injury (BTAI) * Incomplete imaging or follow-up data

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Conditions

The condition(s) this trial relates to.

aortic aneurysm Aortic Dissection familial thoracic aortic aneurysm and aortic dissection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Aortic aneurysm and dissection

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

    Open the record ↗

  2. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

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