Can a nerve block and a sedative replace opioids in heart surgery?
NCT ID NCT07749274
First seen Aug 06, 2026 · Last updated Aug 07, 2026 · Updated 1 time
Summary
This trial compares two anesthesia strategies for minimally invasive heart surgery: one using a sedative called dexmedetomidine plus an ultrasound-guided nerve block, and the other using conventional opioid-based anesthesia. The goal is to see if the new approach allows patients to wake up and breathe on their own sooner after surgery, while also reducing opioid use and related side effects. Adults aged 18-65 scheduled for certain minimally invasive heart procedures may participate.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Dexmedetomidine and an ultrasound-guided erector spinae plane block
- What this could lead to
- If successful, this approach could reduce opioid use and shorten recovery time after minimally invasive heart surgery, potentially leading to faster discharge and fewer opioid-related side effects.
- What could go wrong
- This is a small, early-stage trial, so results may not apply broadly. The nerve block and drug may not work as hoped, and there are always risks with anesthesia and surgery.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Assiut university hospital
Asyut, Ass, 71515, Egypt