Pain relief showdown: ketamine vs fentanyl for gallbladder surgery

NCT ID NCT07670052

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study compares two drugs, ketamine and fentanyl, added to a standard numbing medicine (bupivacaine) to control pain after laparoscopic gallbladder removal. 84 adults aged 20-50 will receive one of the two combinations during surgery. The goal is to see which provides longer-lasting pain relief and reduces the need for additional painkillers.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Ketamine and fentanyl (as adjuvants to bupivacaine)
What this could lead to
If it works, this could point toward a better way to manage pain after gallbladder surgery, reducing the need for strong painkillers.
What could go wrong
This is a small, early-phase trial (84 people) comparing two common drugs, so any benefit may be modest or not apply to everyone. Risks include side effects from the drugs themselves.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

gallstones Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

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Other studies related to the condition(s) this trial covers.