Drinking water may shield kidneys during emergency heart procedures

NCT ID NCT07761754

First seen Aug 12, 2026 · Last updated Aug 13, 2026 · Updated 1 time

Summary

This trial tests whether a structured oral hydration plan—drinking at least 1,500 mL of fluid within 12 hours around the procedure—can reduce the risk of contrast-induced acute kidney injury (CI-AKI) in patients with ST-elevation myocardial infarction (STEMI) undergoing primary PCI. Participants are randomly assigned to either the hydration protocol or standard care. The study measures kidney function via serum creatinine before and after contrast exposure, and monitors for adverse events like fluid overload or heart failure.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
A structured oral hydration protocol with a target intake of at least 1,500 mL within 12 hours around primary PCI, supported by nursing and standardized documentation.
What this could lead to
If effective, this simple, low-cost hydration strategy could become a standard preventive measure to protect kidney function in heart attack patients undergoing stent procedures.
What could go wrong
This is a single-center trial, and the results may not apply broadly. There is also a risk that increased fluid intake could lead to fluid overload or heart failure in some patients.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

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