Cure My Disease

Don't miss your cure!

 Log in / Sign up

Timing of additional artery opening after heart attack could save lives

NCT ID NCT04626882

Ongoing Disease control Sponsor: Chonnam National University Hospital Source: ClinicalTrials.gov ↗

First seen Jul 07, 2026 · Last updated Jul 08, 2026 · Updated 1 time

Summary

This trial looks at the best time to reopen other blocked arteries in people who have just had a major heart attack (STEMI) and have multiple narrowed heart arteries. Participants are randomly assigned to have all blockages fixed right away or in a separate procedure later. A special guidewire (FFR) helps decide which blockages need treatment. The goal is to see which timing leads to fewer deaths, repeat heart attacks, or unplanned procedures over one year.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Fractional flow reserve (FFR)-guided complete revascularization (procedure)
What this could lead to
If it works, this could establish the best timing for treating additional blocked arteries after a heart attack, potentially reducing deaths, repeat heart attacks, and the need for further procedures.
What could go wrong
This is a single-country trial with 994 participants, so results may not apply to all populations. The timing strategy may not improve outcomes and could carry risks like kidney damage from contrast dye.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for MULTI-VESSEL CORONARY ARTERY STENOSIS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

acute myocardial infarction coronary artery disorder coronary stenosis myocardial infarction ST-elevation myocardial infarction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MULTI-VESSEL CORONARY ARTERY STENOSIS MYOCARDIAL INFARCTION, ACUTE

Contacts and locations

Locations

  • Chonbuk National University Hospital

    Jeonju, South Korea

  • Chonnam National University Hospital

    Gwangju, South Korea

  • GangNeung Asan Hospital

    Gangneung, South Korea

  • Gyeongsang National University Changwon Hospital

    Changwon, South Korea

  • Gyeongsang National University Hospital

    Jinju, South Korea

  • Koera University Guro Hospital

    Seoul, South Korea

  • Kyung Hee University Hospital

    Seoul, South Korea

  • Presbyterian Medical Center

    Jeonju, South Korea

  • St. Carollo General Hospital

    Suncheon, South Korea

  • The Catholic University of Korea, Bucheon St. Mary's Hospital

    Bucheon-si, South Korea

  • The Catholic University of Korea, Seoul St. Mary's Hospital

    Seoul, South Korea

  • The Catholic University of Korea, Uijeongbu St. Mary's Hospital

    Uijeongbu-si, South Korea

  • Yeongnam University Medical Center

    Daegu, South Korea

  • Yonsei University, Wonju Severance Christian Hospital

    Wŏnju, South Korea

More trials for these conditions

Other studies related to the condition(s) this trial covers.