Dropping aspirin after a heart attack: a safer path or a risky gamble?
NCT ID NCT07736196
First seen Jul 30, 2026 · Last updated Jul 31, 2026 · Updated 1 time
Summary
This trial tests whether heart attack patients who have had complete artery-opening procedures can safely stop aspirin after 3-6 months and continue with only a P2Y12 inhibitor. The goal is to see if this approach reduces bleeding problems without increasing the risk of another heart attack, stroke, or blood clot. About 300 participants will be randomly assigned to either stop aspirin or stay on standard dual therapy, and researchers will track both bleeding events and cardiovascular outcomes over time.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- aspirin-free strategy with P2Y12 inhibitor monotherapy
- What this could lead to
- If successful, this could lead to a safer, simpler long-term antiplatelet regimen for heart attack patients, reducing bleeding complications.
- What could go wrong
- This is a single-center Phase 4 trial with 300 participants, so results may not apply broadly. Stopping aspirin could increase the risk of blood clots, heart attack, or stroke.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Assiut University Hospital
Asyut, Asyut Governorate, 71515, Egypt
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