One-Dose hormone boost may improve IVF success in frozen embryo transfers

NCT ID NCT07653282

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study investigates whether a single dose of a GnRH agonist (triptorelin) given alongside standard progesterone can improve pregnancy outcomes in women undergoing frozen embryo transfer cycles. The trial includes women aged 20-39 with good quality embryos and normal uterine lining. Researchers will compare clinical pregnancy rates, implantation rates, and live birth rates between those receiving the extra hormone dose and those receiving standard care.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

GnRH agonist (triptorelin)

What this could lead to

If successful, this could offer a simple, single-dose addition to improve pregnancy rates in frozen embryo transfers.

What could go wrong

This is an early-phase study with a moderate sample size, so results may not be conclusive or generalizable. Potential side effects of GnRH agonists include hot flashes and mood changes.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Assiut University

    Asyut, Muslum, Egypt