One-Dose hormone boost may improve IVF success in frozen embryo transfers
NCT ID NCT07653282
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study investigates whether a single dose of a GnRH agonist (triptorelin) given alongside standard progesterone can improve pregnancy outcomes in women undergoing frozen embryo transfer cycles. The trial includes women aged 20-39 with good quality embryos and normal uterine lining. Researchers will compare clinical pregnancy rates, implantation rates, and live birth rates between those receiving the extra hormone dose and those receiving standard care.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- GnRH agonist (triptorelin)
- What this could lead to
- If successful, this could offer a simple, single-dose addition to improve pregnancy rates in frozen embryo transfers.
- What could go wrong
- This is an early-phase study with a moderate sample size, so results may not be conclusive or generalizable. Potential side effects of GnRH agonists include hot flashes and mood changes.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Assiut University
Asyut, Muslum, Egypt