Could a sprinkle of antibiotic powder stop brain shunt infections in kids?

NCT ID NCT07547826

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests whether applying vancomycin powder directly into the surgical wound during shunt placement can prevent infections in children with hydrocephalus. About 164 children will be randomly assigned to receive either standard care or standard care plus the powder. The goal is to see if this simple step reduces infection rates and is cost-effective.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
vancomycin powder
What this could lead to
If it works, this could provide a simple, cheap way to prevent serious infections after shunt surgery in children.
What could go wrong
This is a single-center trial with 164 children, so results may not apply everywhere. Vancomycin powder might not reduce infections significantly, and there is a risk of antibiotic resistance or allergic reactions.

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Conditions

The condition(s) this trial relates to.

Bacterial Infections and Mycoses hydrocephalus Postoperative Complications prosthesis-related infectious disease Surgical Wound Infection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Assiut University, Faculty of Medicine, Assiut University Hospitals, Department of Neurosurgery

    Asyut, Asyut Governorate, 71515, Egypt

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