HYDROCEPHALUS

This study aims to find the best way to prevent infections from a tube (EVD) placed in the brain to drain fluid after a serious brain bleed. Researchers are comparing a single pre-procedure antibiotic dose to a longer course of antibiotics given for the entire time the drain is i…

This study is checking how well and how safely an adjustable valve device works for people with hydrocephalus, a condition where fluid builds up in the brain. The device helps drain excess fluid. Researchers will follow 126 patients for up to 5 years to see if the valve needs rep…

This program provides access to umbilical cord blood infusions for children and young adults (under 26) with brain injuries like cerebral palsy, stroke, or oxygen deprivation. The goal is to use cells from stored cord blood to help the body repair existing brain damage. Participa…

This study is testing a new device that aims to measure pressure inside the skull without needing surgery. Researchers will compare readings from the new, non-invasive device to those from the current surgical method in 581 patients with brain injuries or conditions. The goal is …

This observational study aims to understand how certain markers in brain fluid can help detect infections in patients with acute brain injuries who have drainage tubes. Researchers will monitor 148 patients in Denmark to see if lactate levels in brain fluid can predict infections…

This study aims to collect detailed information from 4,500 patients before and after various brain and spine surgeries. The goal is to identify which factors best predict a patient's recovery and quality of life after their operation. By standardizing how outcomes are measured ac…

This study is testing a new, non-invasive bedside monitor that uses light to measure blood flow and oxygen use in the brains of premature infants. It aims to see if this technology can better track brain health in babies who have had a brain bleed or developed fluid buildup, comp…

This is a laboratory study, not a treatment trial. Researchers are testing if specific mixtures of common numbing medications form crystals when mixed with human spinal fluid. They are using leftover fluid samples from 10 patients with a brain fluid condition. The goal is to unde…

This Mayo Clinic study uses MRI scans to measure how fluid moves around the brain. Researchers want to see if fluid flow differs between healthy adults and people with conditions like Alzheimer's disease or hydrocephalus. The goal is to improve diagnosis and understanding of thes…