POSTOPERATIVE COMPLICATIONS

This study tests a device called the Hypotension Prediction Index (HPI) that warns doctors when a patient's blood pressure is about to drop dangerously low after surgery. 210 adults having elective surgery under general anesthesia will be randomly assigned to either standard moni…

This study tests whether a 20-day fasting schedule before hip replacement surgery can reduce complications like infections. 130 adults will either follow the fasting plan or receive standard care. Researchers will measure changes in gut bacteria and immune markers to see if fasti…

This trial tests whether applying a cold, non-thermal plasma (a kind of energized gas) to the surgical site during standard drainage of a chronic subdural hematoma (a slow brain bleed) can lower the chance it comes back. Forty adults needing surgery will be randomly assigned to g…

This study compares two ways to close the vaginal vault after laparoscopic hysterectomy in women with gynecologic cancers. One method uses a self-locking barbed suture, the other a traditional braided suture. The goal is to see which leads to fewer complications like cuff tears, …

This study is testing a new surgical stapler, called the Signia circular stapler, in people having left-sided colon, sigmoid, or rectal surgery. The goal is to see if it lowers the chance of a leak where the colon is reconnected. About 137 adults will take part, and the main focu…

This study tests whether a vacuum dressing (negative pressure wound therapy) reduces infection compared to standard bandages after skin graft surgery for leg tumors. About 242 adults will be randomly assigned to one of the two dressings. The main goal is to see if the vacuum dres…

This study looks at whether giving patients with bone or soft tissue sarcoma a special nutritional supplement twice daily before surgery can reduce complications and help maintain muscle mass. About 100 adults scheduled for tumor removal will be randomly assigned to receive eithe…

This study tests whether using a reinforcement patch on surgical staplers can lower the risk of leaks and other complications after stomach cancer surgery. About 382 patients will be randomly assigned to receive either the reinforced stapler or a standard stapler during their ope…

This study tests whether adding a protein called albumin to standard IV fluids during a major cancer surgery (cytoreduction with heated chemotherapy) can reduce complications. 140 adults undergoing this surgery will be randomly assigned to receive either standard fluids or standa…

This study compares three breathing therapy devices (EzPAP, Metaneb, and IPPB) to see which one best helps lung recovery after heart surgery. 324 adults who had open-heart surgery will use one of the devices for 10 minutes, four times a day. The goal is to find which therapy impr…

This study tests whether using a smartphone app (Fissios App) for breathing exercises, in addition to in-person physiotherapy, can reduce complications after lung cancer surgery. About 560 adults with non-small cell lung cancer scheduled for surgery will be randomly assigned to e…

This study tests whether a remote expert can guide a bedside ultrasound to detect free fluid (like blood or ascites) in patients who just had liver surgery. Forty participants will receive a telementored eFAST exam, and its accuracy will be compared to standard CT scans and exper…

This study is testing an artificial intelligence tool called DeepComp that uses CT scans and patient data to predict which stomach cancer patients are at high risk for major complications after surgery. Researchers will enroll 500 patients across five medical centers and compare …

This study tests a new imaging technique called iPPG, which uses light to measure blood flow, against the standard method using a green dye (ICG) during gastrointestinal surgery. The goal is to see if iPPG can predict and prevent anastomotic leaks—a serious complication where the…

This study compares four different mouthwashes—Bone Bioactive Liquid, Hyaluronic Acid, Chlorhexidine, and Warm Saline—to see which one helps the healing of tooth sockets after wisdom tooth removal. About 100 adults will be randomly assigned to use one of the rinses. The goal is t…

This study tests whether helping people with insomnia sleep better before knee or hip replacement surgery can reduce pain and improve recovery afterward. One hundred adults scheduled for surgery will receive either cognitive behavioral therapy for insomnia or sleep education for …

This trial tests whether a structured nurse-led education session before prostate cancer surgery, plus a direct referral to pelvic floor physiotherapy, can reduce urinary incontinence afterward. Eighty men having their prostate removed will be randomly assigned to either standard…

This study tests whether playful breathing exercises—like blowing bubbles or cotton balls—can lower anxiety before surgery and reduce confusion after waking up in children aged 3 to 7. About 80 kids will practice these games at home starting 2-3 days before their planned operatio…

This study tests a simple idea: having a parent or family member involved in a child's anesthesia care to reduce emergency delirium—a state of confusion, crying, or thrashing when waking up from surgery. Researchers will compare this family-centered approach to standard care in 4…

This study tests whether a smartphone app that tracks symptoms and gives feedback can help lung cancer patients do their prescribed rehab exercises after minimally invasive surgery. About 736 patients will use the app and be randomly assigned to get symptom alerts with clinician …

This study tests whether tea tree oil mouthwash can reduce pain, swelling, and jaw stiffness after wisdom tooth extraction as well as the standard chlorhexidine mouthwash. Fifty-four adults will use one of the two mouthwashes three times daily for a week after surgery. Researcher…

This study reviews 10 years of medical records from 600 adults who had thyroid surgery at Minia University Hospital. The goal is to find out which patients are most likely to develop low calcium levels after surgery, a common complication. By identifying key risk factors, doctors…

This study looks at when to perform a lung recruitment maneuver—a procedure that reopens collapsed lung areas—during robotic prostate surgery. Researchers will compare doing it before or after the patient is tilted head-down and gas is pumped into the abdomen. The goal is to see …

This study looks at whether a harmless thermal camera can help doctors see how surgical wounds are healing after skin surgery. About 120 adults having skin lesions removed will have their wounds photographed with the camera. The goal is to catch problems like infection or slow he…

This study is testing whether a wearable device can give early warning of complications after chest surgery. The device tracks heart rate, oxygen levels, temperature, and activity from hospital admission to 30 days after discharge. Researchers will first use past data to build a …

This study is building a prediction model to estimate the risk of heart injury after major liver surgery. Researchers will track 1800 patients undergoing hepatobiliary surgery and analyze factors like surgical technique and routine blood tests. The goal is to create a tool that h…

This study observes 10,000 adults undergoing general anesthesia for surgery to see how breathing machines are used and whether they are linked to lung complications. Researchers will track ventilator settings, patient details, and any lung problems or side effects that occur. The…

This study aims to find out if certain substances in the blood can help predict serious complications after high-risk surgeries like heart, lung, or colon operations. Researchers will collect blood samples from about 5,000 patients before and after surgery and track their recover…

This study looks at 500 adults having cancer surgery to see which risk scoring system best predicts if they'll need intensive care afterward. Doctors will calculate scores like ASA and SORT from patient data before and during surgery. The goal is to find the most accurate tool to…

This study will see if an artificial intelligence (AI) model can predict major heart problems within 30 days after gastrointestinal surgery better than current risk scores. Researchers will review medical records of 5,000 adults having surgery at Bach Mai Hospital in 2025-2026. T…

This study aims to create an artificial intelligence (AI) model that can predict complications in children who have a common heart defect called a ventricular septal defect (VSD) repaired with a catheter-based procedure. Researchers will analyze data from over 5,000 children's me…

This study tests a new way to manage fluids during abdominal surgery by watching how the internal jugular vein in the neck changes with breathing. 84 adults having abdominal surgery will be randomly assigned to either standard fluid care or care guided by this vein measurement. T…

This observational study follows 30 women undergoing DIEP flap breast reconstruction after mastectomy. Researchers will measure inflammation and oxidative stress markers in blood samples taken before and after surgery. The goal is to understand how the body responds to the tempor…

This study compares two types of staplers (linear vs circular) used to reconnect the esophagus to the small intestine after stomach removal surgery for gastric cancer. Researchers want to see which stapler leads to fewer complications and shorter surgery time. About 100 adults wi…

This registry is collecting information from 8,000 people undergoing heart or chest surgery. The goal is to see how factors before and during surgery relate to serious complications like death, shock, or infection. By analyzing this data, researchers hope to find ways to improve …

This study is watching 1,200 older adults (65+) before, during, and after surgery to learn why some get complications like confusion (delirium). Researchers will collect blood samples and health information to build a tool that predicts these risks. The goal is to better understa…

This study looks at adults having dental procedures under general anesthesia to see if undiagnosed sleep apnea raises the risk of breathing problems after surgery. Researchers will use two common screening tools (STOP-BANG and ASA criteria) to identify high-risk patients and refe…

This study is observing 42 postoperative patients in the intensive care unit to see if levels of a protein called IL-6 and other inflammation scores can predict who will die or have serious complications. Researchers will measure these markers at ICU arrival and 24 hours later, t…

This study looks at whether showering after surgery while drains are still in place raises the risk of infection or other complications. It will include 100 people having breast reductions or tummy tucks at one medical center. Half will be told they can shower, and half will be t…

This study is looking at whether certain substances in the blood can help predict postoperative delirium—a state of confusion that can occur after surgery in older adults. Researchers will measure specific biomarkers before and after surgery in 1,170 patients aged 65 and older un…

This study is testing whether a special nutrition shake given after surgery can help older adults (70+) regain physical and mental function faster. Half of the 100 participants will receive the shake daily for 30 days, while the other half will follow standard recovery advice. Th…

This study is testing whether a special heart ultrasound can predict who will develop atrial fibrillation after heart surgery. Researchers will measure how well the heart's upper chambers work together before surgery in 138 patients. They will then track patients during recovery …

This study tests whether moving patients to the recovery room before removing their breathing tube frees up the operating room faster after robot-assisted surgery. Researchers will compare two approaches in 218 adults: removing the tube in the operating room versus in the post-an…

This study looks at whether a blood marker called phosphatidylethanol (PEth), which reflects alcohol use over the past few weeks, can predict complications after surgery. Researchers will test PEth levels in 170 adults having elective surgery at University Hospitals Cleveland Med…

This study reviews medical records of 350 adults who had surgery for esophageal cancer in France between 2017 and 2024. Researchers want to understand how often infections happen after surgery, what causes them, and how they affect recovery. The goal is to find ways to prevent th…