Tea tree oil vs. standard mouthwash: a natural remedy for wisdom tooth pain?

NCT ID NCT07180498

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests whether tea tree oil mouthwash can reduce pain, swelling, and jaw stiffness after wisdom tooth extraction as well as the standard chlorhexidine mouthwash. Fifty-four adults will use one of the two mouthwashes three times daily for a week after surgery. Researchers will measure pain levels, mouth opening, and gum healing to see if tea tree oil is a good alternative.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Chlorhexidine gluconate 0.12% mouthwash and tea tree oil mouthwash
What this could lead to
If tea tree oil works as well as chlorhexidine, it could offer a natural alternative for managing pain and swelling after wisdom tooth removal.
What could go wrong
This is a small, early-stage trial with only 54 participants, so results may not apply to everyone. Tea tree oil may cause allergic reactions or be less effective than expected.

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative Postoperative Complications Trismus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Harran University, Faculty of Dentistry

    RECRUITING

    Sanliurfa, Turkey (Türkiye)

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