New Light-Based imaging could replace dye in surgery to prevent dangerous leaks

NCT ID NCT06222645

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a new imaging technique called iPPG, which uses light to measure blood flow, against the standard method using a green dye (ICG) during gastrointestinal surgery. The goal is to see if iPPG can predict and prevent anastomotic leaks—a serious complication where the surgical connection leaks. About 200 adults having elective bowel surgery will be randomly assigned to one of the two imaging methods.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Indocyanine Green (ICG) dye and photoplethysmography (iPPG) imaging

What this could lead to

If successful, this could provide a safer, dye-free way to assess blood flow during surgery, potentially reducing complications like anastomotic leaks.

What could go wrong

This is a single-center trial with 200 participants, so results may not apply broadly. The new iPPG method is still experimental and may not be as accurate as the standard ICG approach.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Anastomotic Leak colorectal cancer colorectal neoplasm digestive system neoplasm gastric cancer gastric neoplasm Postoperative Complications

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Department of Faculty Surgery, Saint Petersburg State University

    RECRUITING

    Saint Petersburg, Leningradskaya Oblast', 199034, Russia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • High-Tech Clinic Beloostrov

    ACTIVE_NOT_RECRUITING

    Saint Petersburg, Leningradskaya Oblast', 197729, Russia

  • Shandong Linglong Yingcheng Hospital

    RECRUITING

    Yantai, Shandong, 265400, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••