GASTRIC CANCER (GC)

This early-stage study tests a new drug called SH009 in about 150 people with advanced solid tumors (like liver, lung, or breast cancer) that have not responded to standard treatments. The main goal is to see if the drug is safe and can shrink tumors. Researchers will also measur…

This study tests whether adding radiation therapy to a combination of chemotherapy and immunotherapy before surgery can improve outcomes for people with resectable stomach or gastroesophageal junction cancer. About 40 participants will be randomly assigned to receive either the s…

This study is for people with stomach cancer that has spread to the lining of the abdomen. It tests a treatment called HIPEC, where heated chemotherapy is given directly into the abdomen during surgery to remove the tumor. The goal is to see if this approach lowers the chance of …

This study tests a new drug combination (iparomlimab and tuvonralimab, called QL1706) plus chemotherapy in people with advanced stomach or gastroesophageal junction cancer that hasn't been treated yet. The goal is to see if the combination shrinks tumors and is safe. About 32 par…

This study compares two chemotherapy drug combinations (oxaliplatin plus S-1 vs. docetaxel plus S-1) in people with stage III stomach cancer who have had surgery to remove the tumor. The goal is to see which combination helps prevent the cancer from coming back for at least 3 yea…

This study tests a combination of three drugs (SHR-1701, rivoceranib, and possibly SHR-2554) in 40 adults with advanced stomach or gastroesophageal junction cancer that has worsened after or was not tolerated during first-line immunotherapy. The goal is to see if the combination …

This study tests a new, non-invasive imaging technique that uses light to measure blood flow during gastrointestinal surgery, comparing it to the standard method that uses a dye called indocyanine green. About 200 adults having elective bowel surgery will be randomly assigned to …

This study tests a new type of PET scan called [18F]FAPI-74 to see if it can better find cancer that has spread in adults with stomach or esophageal cancer. About 200 participants will get one dose of the scan tracer and be followed for up to 3 months. The goal is to see if this …

This study aims to create a blood test that can detect several types of gastrointestinal cancers—like liver, pancreatic, and colon cancer—at an early stage. Current screening methods are often invasive or not sensitive enough. The test looks for tiny molecules called miRNAs in th…

This study looks at how far surgeons should go when removing lymph nodes near the stomach during surgery for advanced stomach cancer. About 400 people having this surgery will take part. The goal is to find the best balance between removing enough lymph nodes and avoiding unneces…

This study looks at 400 people having surgery for stomach or junction cancer. After removing the upper part of the stomach, doctors reconnect the digestive tract in different ways. The goal is to find which method causes fewer problems like acid reflux, trouble swallowing, and po…