New chemo combo could improve outcomes for stomach cancer patients

NCT ID NCT07366528

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase 3 trial tests whether a chemotherapy combination of oxaliplatin plus S-1 works as well as or better than docetaxel plus S-1 for stage III gastric cancer patients who have had surgery. About 387 adults aged 18 to 80 will be randomly assigned to one of the two treatments. The main goal is to see how many patients remain cancer-free after three years.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

oxaliplatin plus S-1 or docetaxel plus S-1

What this could lead to

If successful, this could identify a more effective or less toxic chemotherapy option for stage III gastric cancer patients after surgery.

What could go wrong

This is a non-inferiority trial, so the new combo may not be better than the standard. Side effects from chemotherapy are expected and can be serious.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

gastric adenocarcinoma gastric cancer gastric neoplasm neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Fudan University Shanghai Cancer Center

    NOT_YET_RECRUITING

    Shanghai, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Renji Hospital

    NOT_YET_RECRUITING

    Shanghai, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Ruijin Hospital

    RECRUITING

    Shanghai, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Shanghai Tenth People's Hospital

    NOT_YET_RECRUITING

    Shanghai, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Yuebei People's Hospital

    NOT_YET_RECRUITING

    Shaoguan, Guandong, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••