POSTOPERATIVE COMPLICATIONS

This trial tests whether a program of exercise, nutrition advice, and psychological support—started four weeks before surgery and continued afterward—can reduce complications in people having colon cancer surgery. Participants are adults over 40 with non-metastatic colon cancer w…

This study looked at whether giving fluids (colloids or crystalloids) before general anesthesia can prevent low blood pressure and reduce complications within 30 days after non-cardiac surgery. Over 2,000 adults having elective surgery took part. The goal was to see if this simpl…

This study tested a new way to set the breathing machine during back surgery. Instead of using standard settings, doctors adjusted the machine based on how stiff the patient's lungs were. The goal was to see if this approach could reduce lung problems after surgery. The study inv…

This study tested a special collagen mesh for hernia repair in 30 patients who were at high risk for complications, such as those with diabetes or infections. The mesh is designed to be absorbed by the body and help tissue heal naturally, avoiding problems linked to permanent syn…

This study looked at whether lowering the use of anticholinergic drugs—common in older adults and linked to confusion and frailty—before and after heart surgery can help patients recover better. Researchers studied 120 adults having elective coronary artery bypass surgery. They m…

This large international trial tested whether keeping a patient's blood flow (cardiac index) at their own personal baseline during major abdominal surgery reduces serious complications. Over 1,100 high-risk adults aged 45 and older took part. The goal was to see if this personali…

This study tested whether adjusting a ventilator's pressure settings to each patient could reduce lung complications in older adults after upper abdominal keyhole surgery. 136 patients aged 60-80 took part. The approach aims to improve oxygen levels and lower the risk of pneumoni…

This completed trial tested whether using a continuous vital sign monitor (GE Portrait) with nursing alerts could reduce dangerous changes in oxygen, breathing, and heart rate after major noncardiac surgery. 227 adults were monitored either openly or with the data hidden. The goa…

This study tested whether doing special breathing exercises before abdominal surgery could lower the number and severity of complications after the operation. 134 adults scheduled for major belly surgery took part. They practiced breathing with a device to strengthen their breath…

This study looked at whether taking ibuprofen for eight days after hip or knee replacement surgery is safe. Over 2,900 adults were randomly given either ibuprofen or a placebo. Researchers tracked serious problems like heart attack, stroke, blood clots, kidney failure, and bleedi…

This trial investigates whether drinking coffee after pancreatic surgery can help the bowel start working again sooner. About 200 adults who had open pancreatic surgery will receive either regular coffee, decaf coffee, or water twice a day. The main goal is to see how quickly the…

This study compared two types of breathing tubes (Air-Q and Proseal LMA) in 97 elderly patients aged 65-90 undergoing surgery. The goal was to see which device works better and causes fewer side effects like sore throat. Researchers measured how well each tube sealed the airway a…

This study looked at two ways to manage pain after a planned C-section: a nerve block (TAP block) and injecting pain medicine into the wound. 75 women took part. The goal was to see which method helps mothers feel better and recover more quickly after surgery.

This study tested how comfortable two prescription steroid eye drops feel right after use. Forty adults with eye inflammation or dry eye received one drop of Flarex in one eye and one drop of Lotemax SM in the other. They rated comfort and vision impact at 30 seconds, 5 minutes, …

This study tested whether two types of nerve blocks (SAP and PECS) can reduce pain and shorten the time patients need a breathing tube after heart bypass surgery. 243 adults undergoing open heart surgery received either a nerve block or standard pain medication. Researchers measu…

This study looked at whether the usual advice to rest for 6 weeks after a C-section is really needed. 200 women were randomly assigned to either follow standard activity restrictions or start a gentle 10-week exercise program. The goal was to see if exercise could improve overall…

This study looked at 102 children who had surgery for a heart problem present at birth. After surgery, they were placed on their stomachs with their heads raised at different angles (10°, 30°, or 45°) to see which angle best helped their heart and lungs recover. The goal was to f…

This study looked at whether Emotional Freedom Technique (EFT), a therapy that involves tapping on specific body points, can reduce death anxiety in people who have had cancer surgery. 120 adults who had oncological surgery and had no prior psychiatric issues took part. The goal …

This study tested whether abdominal acupuncture can help women recover normal bowel function faster after gynecologic laparoscopic surgery. 80 women who had a hysterectomy participated. Researchers measured how quickly they passed gas and had their first bowel movement after surg…

This study tested whether adding interactive videos to standard care improves quality of life and recovery in patients with early postoperative bowel obstruction. 462 adults who had abdominal surgery were randomly assigned to either standard care alone or standard care plus a ser…

This study tested whether using cold saline (0-4°C) instead of room-temperature saline during wisdom tooth removal reduces pain, swelling, and jaw stiffness. Fourteen healthy adults with two impacted wisdom teeth had one tooth removed with cold saline and the other with room-temp…

This completed trial tested whether a combination of four non-opioid drugs (magnesium, dexmedetomidine, ketamine, and lidocaine) given during major surgery could improve patient recovery compared to standard opioid-only anesthesia. 240 adults undergoing planned major surgery were…

This study tested whether a Post-Dental Extraction Care Kit (PDEC-kit) helps patients better understand and follow care instructions after a tooth extraction, and whether it reduces anxiety. 208 adults having routine tooth removal were split into two groups: one received standard…

This study looked at 393 older adults (65+) who went to the intensive care unit after surgery. Researchers checked their frailty level, ability to do daily tasks, and routine blood tests when they arrived. The goal was to see if these simple measures could predict who might die i…

This study looked at 44,000 adults who had general anesthesia for non-heart surgeries using a supraglottic airway device (a type of breathing mask). The goal was to use artificial intelligence to predict, before surgery, which patients might need an emergency switch to a breathin…

This study looked at whether checking patients by phone before surgery leads to more cancellations than checking them in person. Researchers reviewed records of 1176 adults scheduled for non-cardiac surgery at two hospitals. The goal was to see if phone assessments are a safe and…

This completed trial tested whether using positive pressure while removing the breathing tube (extubation) can prevent low oxygen levels after abdominal surgery. 264 adults undergoing scheduled visceral or urological surgery were randomly assigned to standard extubation or one of…

This study examines whether frailty and simple blood tests can predict which patients aged 80 and older are most likely to die within 30 days after major abdominal surgery. Researchers will review records of 100 patients to see if a frailty index and lab markers like albumin and …

This study looked at 200 older adults (65+) having planned surgery for colorectal cancer. Researchers used a frailty test before surgery to see if it could predict complications like infections or longer hospital stays. The goal is to help doctors better plan care and reduce risk…

This study looked at 330 older adults (65+) who had cancer surgery to see if low albumin levels before surgery led to more complications. Researchers compared patients with low albumin to those with normal levels, tracking problems like infections, hospital stay length, and ICU n…

This study tested whether a tool called the ARISCAT score can predict lung complications (like pneumonia or collapsed lung) after major abdominal cancer surgery. Researchers followed 410 adults who had surgery under general anesthesia. The goal was to see if the score could help …

This study observed over 6,400 adults undergoing elective surgery to see how doctors prescribe sugammadex, a drug that reverses muscle paralysis from anesthesia. Researchers collected data from routine care, without extra tests or treatments. The goal was to understand prescripti…

This study tested whether giving 50% or 100% oxygen before removing a breathing tube after anesthesia leads to fewer drops in oxygen levels. 119 patients were monitored after surgery. The goal is to find the safest oxygen setting to prevent breathing problems during recovery.

This study reviewed medical records of 901 infants who had surgery for aortic coarctation (a narrowed aorta) before age one. Researchers wanted to find out how many later developed high blood pressure or re-narrowing of the aorta. The goal is to better understand these risks and …

This study looked at whether using EEG brain-wave monitoring during general anesthesia helps doctors give the right amount of medicine. The goal was to help patients wake up faster after surgery and reduce memory or thinking problems. About 100 adults having surgery took part. Re…

This study looked at whether using continuous non-invasive blood pressure monitoring during surgery could reduce the risk of organ failure after surgery, compared to standard intermittent monitoring. Over 1,200 adults having non-cardiac surgery took part. The main focus was on pr…

This study reviewed 148 patients who had thigh bone or hip replacement-related fracture surgery using metal wires (cerclage) to hold bone pieces together. Researchers found that using more wires was linked to a higher chance of deep infections and prolonged wound drainage. The fi…

This completed study looked at 300 liver transplant cases to understand why donor livers with fatty liver disease are more likely to be injured after transplantation. Researchers compared genetic activity in archived tissue samples from 50 cases, using advanced techniques to iden…

This study tested whether using low tidal volume ventilation (gentle breathing) during heart-lung bypass surgery could help doctors spot early kidney stress. Researchers measured kidney blood flow with ultrasound in 60 patients after surgery. The goal was to see if this breathing…

This study followed 240 high-risk surgery patients to see if problems in the recovery room (PACU) are linked to complications in the first 72 hours after leaving. Researchers tracked vital signs and medical events, and also asked nurses to assess risk. The goal is to find early w…

This study reviewed the medical records of 239 patients aged 65 and older who had major abdominal surgery. The goal was to find out what factors increase the risk of lung complications like pneumonia or respiratory failure after surgery. By understanding these risks, doctors may …

This study checked if a simple risk model (ExCARE) can accurately predict which patients might die within 30 days after non-cardiac surgery. Researchers looked at 3,000 adults having elective or emergency surgery at a Brazilian hospital. No treatments or changes to care were give…

This study looked at 8,751 patients aged 65 and older who had elective non-cardiac, non-brain surgery. Researchers examined how patients' health and daily function before surgery related to serious heart and brain complications within 30 days after surgery. The goal was to compar…

This completed study tested whether a liver ultrasound could detect right-sided heart failure after cardiac surgery. Researchers measured blood flow in the portal vein using Doppler ultrasound in 32 high-risk patients within 24 hours of surgery. The goal was to see if this simple…

This study tested two simple breathing maneuvers—briefly pausing the ventilator at different points—to see if they could predict whether a patient needs more fluids after heart surgery. 90 adults on ventilators after cardiac surgery were included. The goal was to find a reliable,…

This study analyzed health records from over 400,000 adults who had heart surgery to see if the sedative dexmedetomidine helped prevent problems like confusion, kidney injury, or death within 30 days. Researchers compared patients who received the drug around surgery time to thos…

This study looked at over 2,300 children aged 0-12 who had mild cold symptoms before elective non-cardiac surgery. Researchers wanted to see if the COVID-19 pandemic changed the risks of complications like breathing problems or infections. The goal is to help doctors decide the s…

This study looked at whether lung ultrasound can predict if elderly patients (65+) will need breathing support again after their breathing tube is removed following surgery. Researchers followed 130 patients and checked ultrasound scores, diaphragm movement, and oxygen levels. Th…