Scientists probe genetic secrets of fatty liver transplants

NCT ID NCT07362745

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed study looked at 300 liver transplant cases to understand why donor livers with fatty liver disease are more likely to be injured after transplantation. Researchers compared genetic activity in archived tissue samples from 50 cases, using advanced techniques to identify which cells and genes play a role. The goal is to find molecular clues that could help predict transplant success and improve donor liver selection.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could help doctors better predict which fatty livers are safe to transplant, potentially expanding the donor pool and reducing waitlist deaths.

What could go wrong

This is a retrospective analysis of existing data, not a treatment trial. Findings may not translate into immediate clinical changes, and the small number of tissue samples (50) limits how broadly the results can be applied.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for END STAGE LIVER DISEASE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

chronic liver failure End Stage Liver Disease fatty liver disease liver failure Postoperative Complications

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Department of Hepatobiliary Surgery, Xijing Hospital, Air Force Medical University

    Xi'an, Shaanxi, 710032, China