Xijing Hospital

This early-phase study tests a new immunotherapy drug (QL1706) combined with short cycles of chemotherapy for people with early-stage triple-negative breast cancer (TNBC). TNBC is an aggressive cancer that lacks common targets, making it harder to treat. The trial will enroll 30 …

This study tests a daily pill called ivarmacitinib in 60 adults with palmoplantar pustulosis (PPP), a long-term skin condition causing painful blisters on hands and feet. Participants take one 4mg pill daily for 12 weeks. Researchers will check if symptoms improve by at least 50%…

This study explores whether a low branched-chain amino acid diet (a type of protein-restricted diet) combined with an immunotherapy drug (anti-PD-1) is safe and effective for people with stage III melanoma that has spread to lymph nodes. About 80 participants will receive the die…

This early study tests whether stimulating a nerve in the lower back (sacral nerve stimulation) can safely reduce symptoms of ulcerative colitis. It includes 15 adults whose colitis is moderate-to-severe and hasn't improved with standard drugs. The main goal is to see if the trea…

This study tests whether adding the drug serplulimab to standard chemotherapy before surgery can better shrink advanced stomach or gastroesophageal junction cancer. About 116 adults will receive either the combination or chemo alone for three cycles before and after surgery. The …

This early study tests a drug called meplazumab in 18 people with stable coronary artery disease. The drug targets a protein linked to inflammation that may worsen artery plaques. Researchers will use CT scans and blood tests to see if the drug reduces inflammation and plaque bui…

This study tests a new 3D-printed biodegradable mesh used during breast reconstruction after mastectomy for breast cancer. The goal is to see if it improves cosmetic results and patient satisfaction while being safe. About 25 women aged 18-70 who need a full mastectomy and choose…

This study tests a drug called picankibart in 60 adults with moderate-to-severe palmoplantar pustulosis, a skin condition causing painful pus-filled blisters on hands and feet. Participants must have tried other treatments without success. The goal is to see if the drug reduces t…

This study compares a new dissolvable scaffold (Firesorb) to a standard metal stent for treating blocked heart arteries. The scaffold is designed to support the artery temporarily and then dissolve, potentially avoiding long-term problems linked to permanent stents. About 2,000 p…

This study tests whether the inhaled anesthetic desflurane is better than the IV drug propofol at preventing major heart events like death, heart failure, or heart attack in adults undergoing coronary artery bypass surgery. About 3,560 participants will be randomly assigned to re…

This study aims to see if a special PET scan (68Ga-PSMA) is better than standard CT scans at finding where kidney cancer has spread in the body. About 300 adults with advanced kidney cancer will receive both scans, and doctors will compare the results. If the PET scan proves more…

This study is testing a new blood test that looks for tiny genetic particles (exoRNA) to find clinically significant prostate cancer. The goal is to see if this test can accurately diagnose the disease and reduce the need for invasive biopsies. The study will involve 1700 men wit…

This study is developing a blood test that looks at genetic material from tiny particles (exosomes) to predict if prostate cancer has spread to the bones. Researchers will enroll 1,000 men with newly diagnosed prostate cancer to see if the test can accurately rule out bone metast…

This study looks at whether waiting 2-3 hours after injection before doing a PSMA PET scan can better find aggressive prostate cancer compared to the usual 1-hour wait. About 1000 men with suspected prostate cancer will get both scans, and results will be compared to biopsy findi…

This study tests whether a device called TENS, which sends mild electrical pulses through the skin, can safely reduce pain and improve daily function in adults with long-term low back pain. Forty participants will use TENS five times a week for four weeks. Researchers will track …

This study tests whether a gentle magnetic pulse to the cerebellum can improve memory and thinking in people with mild Alzheimer's disease. About 100 adults aged 50-85 will receive either real or fake stimulation over three months. The goal is to see if this safe, non-invasive tr…

This study tests whether a non-invasive brain stimulation technique called transcranial magnetic stimulation (TMS) can improve recovery in people who have had a stroke and undergone a procedure to remove a blood clot. About 60 adults aged 18-80 with a specific type of stroke will…

This early-stage study tests whether a medicine made from horse chestnut extract (sodium aescinate) can safely reduce pain in adults with long-term low back pain. About 40 people will take either the drug or a placebo for a short time, and researchers will measure changes in pain…

This study tests whether a numbing injection near the neck nerves (stellate ganglion block) given before coronary bypass surgery can lower the chance of developing atrial fibrillation, a fast and irregular heartbeat, after the operation. About 60 adults having bypass surgery will…

This study looks at why many people with ulcerative colitis have trouble sleeping and how that affects their disease. Researchers will track sleep quality, gut bacteria, and nerve activity in 152 patients. The goal is to understand the connection between the gut and brain to impr…

This study looks at whether changes in DNA markers in the blood can show how well esophageal cancer responds to treatment. Researchers will compare these markers with standard scans and tumor tests in 300 adults. The goal is to find a faster, less invasive way to guide treatment …

This study asks 600 heart patients and their doctors which treatment they prefer for blocked arteries: a permanent metal stent or a drug-coated balloon that dissolves over time. The goal is to understand how much extra risk people are willing to accept to avoid having a metal imp…

This study follows 1,500 adults having planned heart surgery to learn why some become confused or delirious afterward and how that affects their recovery. Researchers will track factors before surgery and check patients' mental status after. No new treatments are tested; the goal…

This study looks at whether a special type of PET scan (PSMA PET) can better track how well prostate cancer treatment is working. It involves 110 men with newly diagnosed, aggressive prostate cancer. They will get a PSMA PET scan before treatment and another one after treatment t…

This study aims to see if a special type of PET scan (PSMA PET) can predict how prostate cancer will progress in people who have just been diagnosed and haven't started treatment yet. Researchers will follow 1,000 participants for at least 2 years to track cancer growth or return…

This study looks at whether the anesthetic propofol can lower the risk of postoperative delirium (sudden confusion after surgery) compared to sevoflurane in diabetic patients aged 60 and older. About 450 people having non-cardiac surgery will be randomly assigned to receive one o…

This study looks at how taking multiple medications affects the health of elderly people with chronic diseases like heart disease, diabetes, and high blood pressure. Researchers will survey 2000 patients aged 65 and older in Shaanxi Province, China, over two years. The goal is to…

This study compares how heart disease patients and healthcare providers weigh the importance of different health events, like heart attack or stroke, compared to death. Researchers want to see if patients and doctors value these events differently, which could help design better …