Can a simple protein improve recovery from heated chemo surgery?

NCT ID NCT06351475

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether adding a protein called albumin to standard IV fluids during a major cancer surgery (cytoreduction with heated chemotherapy) can reduce complications. 140 adults undergoing this surgery will be randomly assigned to receive either standard fluids or standard fluids plus albumin. The main goal is to see if the albumin group has fewer complications 28 days after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

20% human albumin

What this could lead to

If it works, this could lead to a safer fluid management strategy during complex cancer surgery, reducing postoperative complications.

What could go wrong

This is a relatively small, early-stage trial (140 patients) testing a well-known drug in a new setting. The benefit may be small or not seen at all, and albumin is expensive with potential allergic reactions.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

peritoneal carcinomatosis peritoneal neoplasm Postoperative Complications

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Gustave Roussy Institute

    RECRUITING

    Villejuif, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hôpital Hautepierre / UIC ARMO

    RECRUITING

    Strasbourg, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Institut régional du Cancer de Montpellier

    RECRUITING

    Montpellier, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • La Pitié Salpetriere hospital

    RECRUITING

    Paris, 75013, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Lariboisière hospital

    RECRUITING

    Paris, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Robert Debré hospital

    RECRUITING

    Reims, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Saint Louis hospital

    RECRUITING

    Paris, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••