Can too much fluid harm ICU patients? a global investigation

NCT ID NCT06258616

First seen Aug 10, 2026 · Last updated Aug 11, 2026 · Updated 1 time

Summary

This international study observes how fluids are administered to critically ill adults in intensive care units (ICUs) and how often fluid accumulation occurs. Researchers will track fluid balance, body weight changes, and clinical signs like swelling to understand risk factors and outcomes. The goal is to provide a clearer picture of fluid management practices and their impact on patient recovery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
This research could lead to better guidelines for fluid management in intensive care, potentially improving recovery and reducing complications from fluid overload in critically ill patients.
What could go wrong
As an observational study, it cannot prove cause and effect. Findings may not apply to all ICUs or patient groups, and fluid accumulation estimates may vary between clinicians.

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Conditions

The condition(s) this trial relates to.

Edema

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Deparment of Intensive care, Nordsjællands hospital

    Hillerød, Hillerød, 3400, Denmark

  • Departmen of Intensive Care

    Aalborg, 9000, Denmark

  • Department of Anaesthesia and Critical Care Vilnuis University Hospital Santariskiu Cinics, Vilnuis

    Vilnius, Lithuania

  • Department of Anaesthesiology, Critical Care and Pain Tata Memorial Hospital, Mumbai.

    Mumbai, India

  • Department of Intensive Care Wellington Hospital (CCDHB), Newton, Wellington

    Wellington, New Zealand

  • Department of Intensive Care, Bispebjerg

    Copenhagen, 7100, Denmark

  • Department of Intensive Care, Herlev Hospital

    Herlev, 2730, Denmark

  • Department of Intensive Care, Inselspital

    Bern, Switzerland

  • Department of Intensive Care, Landspitali National University Hospital of Iceland

    Reykjavik, Iceland

  • Department of Intensive Care, Regionshospital Gødstrup

    Herning, 7400, Denmark

  • Department of Intensive Care, Regionshospitalet Randers

    Randers, 8930, Denmark

  • Department of Intensive Care, Rigshospitalet 4131

    Copenhagen, 2100, Denmark

  • Department of Intensive Care, Stavanger University Hospital

    Stavanger, 4068, Norway

  • Department of Intensive Care, Sygehus Sønderjylland Aabenraa

    Aabenraa, Denmark

  • Department of Intensive Care, Tampere University Hospital

    Tampere, 33520, Finland

  • Department of Intensive Care, University Hospital Zealand, Roskilde

    Roskilde, Denmark

  • Department of Intensive Care, University hospital Aarhus

    Aarhus, Denmark

  • Department of Intensive Care, Zealand University hospital

    Køge, 4600, Denmark

  • General Adult Intensive Care Unit, Critical Care Directorate University Hospital of Wales, Cardiff

    Cardiff, United Kingdom

  • Helsingborg Hospital

    Helsingborg, Sweden

  • Hospital Clinic of Barcelona

    Barcelona, Spain

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