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Ultrasound-Guided fluid removal may offer safer relief for overloaded kidneys

NCT ID NCT07705269

Recruiting now Disease control Sponsor: Universidad Autonoma de Nuevo Leon Source: ClinicalTrials.gov ↗

First seen Jul 15, 2026 · Last updated Jul 16, 2026 · Updated 1 time

Summary

This study tests whether a personalized, high-rate fluid removal strategy guided by ultrasound is as safe and effective as the standard rate for patients with advanced kidney disease hospitalized due to severe fluid overload. Participants are randomly assigned to receive either a standard fluid removal rate or a higher rate, with ultrasound used to guide treatment. The goal is to see if the higher rate can relieve symptoms like shortness of breath more quickly without causing dangerous drops in blood pressure.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
high-rate ultrafiltration (fluid removal during hemodialysis) guided by ultrasound
What this could lead to
If successful, this approach could offer a safer, faster way to relieve severe fluid overload in hospitalized kidney patients, potentially reducing breathing difficulties and hospital stays.
What could go wrong
This is a small, early-stage trial with only 70 participants, so results may not apply to all patients. The high fluid removal rate could increase the risk of sudden drops in blood pressure.

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Conditions

The condition(s) this trial relates to.

chronic renal failure syndrome congestive heart failure Edema end stage renal failure heart failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CONGESTIVE HEART FAILURE (CHF) END STAGE CHRONIC RENAL FAILURE FLUID OVERLOAD INTRAVASCULAR CONGESTION

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Hospital Universitario "Dr. José E. González"

    RECRUITING

    Monterrey, Nuevo León, 64460, Mexico

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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