New ultrasound technique could predict kidney transplant success without needles

NCT ID NCT07645599

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This pilot study tests a new ultrasound imaging method called Super-Resolution Ultrasound (SRU) to look at blood flow in tiny vessels of transplanted kidneys. The goal is to see if changes in these vessels can predict how well the kidney will work early after transplant, including delayed function. The study involves 40 adult kidney transplant recipients and uses an FDA-approved contrast agent. If it works, this could become a safe, noninvasive way to check kidney health without biopsies.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Ultrasound contrast agent (lipid microspheres) and super-resolution ultrasound imaging

What this could lead to

If successful, this imaging technique could help doctors predict how well a transplanted kidney will work early on, reducing the need for invasive biopsies.

What could go wrong

This is a very small pilot study (40 people) testing a new imaging method, so it may not prove reliable or widely useful. The technique is still experimental and not yet ready for routine use.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

chronic renal failure syndrome Delayed Graft Function end stage renal failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

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  • Contact

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Locations

  • University of Pittsburgh Medical Center

    Pittsburgh, Pennsylvania, 15213, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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