Scientists probe immune cells to predict transplant rejection

NCT ID NCT03016455

Completed Knowledge-focused Sponsor: University Hospital, Brest Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed study looked at 116 kidney transplant patients to understand how B cells (a type of immune cell) behave in those who develop donor-specific antibodies or chronic rejection. Researchers analyzed blood samples to find patterns that could serve as early warning signs. The goal is to improve future treatments by identifying who is at risk.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could lead to better ways to predict and treat antibody-mediated rejection in kidney transplant patients.
What could go wrong: This is an observational study, not a treatment trial. It may not directly lead to new therapies, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

chronic transplant rejection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

RENAL TRANSPLANT

Contacts and locations

Locations

APHP Hôpital Necker

Paris, 75743, France
CHU Amiens

Amiens, 80054, France
CHU Brest

Brest, 29200, France
CHU CAEN

Caen, 14033, France
CHU Limoges

Limoges, 87042, France
CHU Poitiers

Poitiers, 86021, France
CHU Reims

Reims, 51092, France
CHU Rennes

Rennes, 35033, France
CHU Rouen

Rouen, 76230, France
CHU Tours

Tours, 37044, France
Chu Angers

Angers, 49933, France
Chu Clermont Ferrand

Clermont-Ferrand, 63003, France
Hôpitaux Universitaires de Strasbourg

Strasbourg, 67091, France

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