FLUID OVERLOAD

This study looks at whether a drug called furosemide (a water pill) can safely help intensive care patients who have too much fluid in their bodies. About 1000 adults will be randomly assigned to receive either furosemide or a placebo until the extra fluid is gone. The goal is to…

This study compares two approaches to removing excess fluid in intensive care patients with acute kidney injury who are on dialysis. One group will have fluid removed at a moderate rate to actively reduce fluid buildup, while the other group will have fluid removed slowly to just…

This study tests whether using lung ultrasound to guide removal of extra fluid helps patients on breathing machines in the ICU breathe on their own sooner. About 1,000 adults who need a ventilator for at least another day will be randomly assigned to have fluid removal guided by …

This study looks at how much fluid patients should receive during robotic prostate surgery. It compares a standard approach with a more restricted one, using a non-invasive heart monitor to guide decisions. The goal is to see which method keeps tissues better perfused, measured b…

This pilot study tests whether an AI-based system can help doctors better manage fluids and blood pressure during complex ovarian cancer surgery. The system uses special software to guide fluid infusions and predict drops in blood pressure. The goal is to reduce complications lik…

This study compares three ways to check for fluid overload (too much fluid in the body) in people doing dialysis at home. Researchers will ask about symptoms, do a physical exam, and use a safe ultrasound of the lungs. The goal is to find which method works best to help prevent h…

This study observes 150 ICU patients who need excess fluid removed. Researchers will track how fast and when fluid is removed, and look for signs of success or side effects like low blood pressure. The goal is to find safer, more personalized fluid removal methods, but this study…

Researchers at the University of Michigan and Northwestern University are interviewing children, adults, and parents of young children about their experiences with swelling caused by Nephrotic Syndrome. The goal is to develop a survey that can be used in future clinical trials to…

This study reviews medical records from over 50,000 critically ill patients to see if starting dialysis earlier helps them live longer. Researchers will compare patients who started dialysis early versus late, looking at survival up to 90 days and beyond. The goal is to find the …