FLUID OVERLOAD
Clinical trials for FLUID OVERLOAD explained in plain language.
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New pill timing may help heart failure patients flush salt after meals
Disease control CompletedThis study tested whether an extended-release version of the diuretic torsemide helps heart failure patients get rid of more salt after lunch compared to the standard immediate-release version. Twenty adults with stable heart failure took both forms in a random order, and researc…
Matched conditions: FLUID OVERLOAD
Phase: PHASE4 • Sponsor: Sarfez Pharmaceuticals, Inc. • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC
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New dialysis strategy aims to prevent fluid overload in critical care
Disease control CompletedThis study tested a method to carefully remove extra fluid from critically ill patients with kidney failure who are on continuous dialysis. The goal was to keep their fluid levels balanced without causing dangerous drops in blood pressure. Researchers used advanced heart monitori…
Matched conditions: FLUID OVERLOAD
Phase: NA • Sponsor: Hospices Civils de Lyon • Aim: Disease control
Last updated Jun 27, 2026 07:58 UTC
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Could a simple shot replace the IV for heart failure fluid removal?
Knowledge-focused CompletedThis early-stage study tested a new version of the water pill furosemide that can be injected under the skin (subcutaneous) using an autoinjector, comparing it to the standard IV form given in a hospital. The study involved 21 healthy volunteers aged 45 to 80 to see how the drug …
Matched conditions: FLUID OVERLOAD
Phase: PHASE1 • Sponsor: scPharmaceuticals, Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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New ultrasound technique may prevent fluid overload in ICU patients
Knowledge-focused CompletedThis study looked at whether measuring the inferior vena cava through the liver (transhepatic approach) can predict if a patient needs more fluids after heart surgery. 40 ICU patients were included. The goal was to avoid giving too much fluid, which can be harmful. The study comp…
Matched conditions: FLUID OVERLOAD
Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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Simple breath holds may help doctors avoid fluid overload after heart surgery
Knowledge-focused CompletedThis study tested two simple breathing maneuvers—briefly pausing the ventilator at different points—to see if they could predict whether a patient needs more fluids after heart surgery. 90 adults on ventilators after cardiac surgery were included. The goal was to find a reliable,…
Matched conditions: FLUID OVERLOAD
Phase: NA • Sponsor: Tanta University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC
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ICU dialysis study seeks sweet spot for fluid removal
Knowledge-focused CompletedThis study looked at 39 intensive care patients with acute kidney failure who needed dialysis to remove excess fluid. Researchers tested three different fluid removal rates (1, 2, and 3 ml per kg per hour) to see which caused the fewest drops in blood pressure while still effecti…
Matched conditions: FLUID OVERLOAD
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC