ICU kidney trial aims to find best fluid removal rate
NCT ID NCT05817539
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares two approaches to removing excess fluid in intensive care patients with acute kidney injury who are on dialysis. One group will have fluid removed at a moderate rate to actively reduce fluid buildup, while the other group will have fluid removed slowly to just maintain current levels. The goal is to see which strategy leads to fewer days on life support and better recovery. The trial plans to enroll 250 adults in the ICU.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
ultrafiltration (fluid removal) procedure
What this could lead to
If successful, this could establish a safer, more effective way to remove excess fluid in ICU patients on dialysis, potentially reducing time on life support and improving survival.
What could go wrong
This is a moderate-sized early-stage trial, so results may not apply to all ICU patients. Aggressive fluid removal can cause low blood pressure or organ injury, and the benefit over standard care is unproven.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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CHU Amiens-Picardie
NOT_YET_RECRUITINGAmiens, 80480, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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CHU Caen Normandie
NOT_YET_RECRUITINGCaen, 14033, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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CHU Lille - Hôpital Roger Salengro
NOT_YET_RECRUITINGLille, 59037, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Centre Hospitalier d'Ajaccio
NOT_YET_RECRUITINGAjaccio, 20090, France
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Département d'anesthésie réanimation Hôpital Européen Georges Pompidou
RECRUITINGParis, 75015, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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GHP Saint Joseph Marie Lannelongue
NOT_YET_RECRUITINGLe Plessis-Robinson, 92350, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Hôpital Edouard Herriot
NOT_YET_RECRUITINGLyon, 69437, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Hôpital Edouard Herriot, Groupement Hospitalier Centre
RECRUITINGLyon, 69003, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Hôpital de la Croix Rousse
NOT_YET_RECRUITINGLyon, 69004, France
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Hôpital de la Croix Rousse
RECRUITINGLyon, 69004, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Hôpitaux de Bradois - CHRU Nancy
NOT_YET_RECRUITINGVandœuvre-lès-Nancy, 54511, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Service d'Anesthesie-Réanimation, Hôpital Louis Pradel, Hospices Civils de Lyon
RECRUITINGBron, 69500, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Service de Réanimation, CHU de Dijon
RECRUITINGDijon, 21000, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Service de Réanimation, Clinique de la Sauvegarde
RECRUITINGLyon, 69009, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact