New blood test score could personalize heart failure diuretic use

This trial tests whether a new scoring system, called the Biological Congestion Score (BCS), can help doctors better manage diuretic medications in people with chronic heart failure. The BCS combines four blood biomarkers with clinical information to estimate fluid congestion and risk. Researchers will compare outcomes like death, heart failure events, and quality of life between patients whose diuretic therapy is guided by the BCS and those receiving standard care. The study plans to enroll 600 adults with symptomatic heart failure who are already taking diuretics.