Can Lab-Grown tumor models predict the best therapy for each patient?

NCT ID NCT05844865

First seen Aug 14, 2026 · Last updated Aug 14, 2026

Summary

This pilot study aims to create personalized, lab-grown models of tumors from patients with gastrointestinal peritoneal carcinomatosis. Researchers will collect blood, ascites fluid, and tumor samples during planned surgeries to build vascularized micro-tumors. These models could help test how well different treatments work for each individual, potentially guiding more effective therapy choices.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Biospecimen collection (blood, ascites/peritoneal wash fluid, and tumor samples) during planned surgery
What this could lead to
If successful, this could lead to personalized lab-grown tumor models that help predict which treatments work best for individual patients with gastrointestinal peritoneal carcinomatosis.
What could go wrong
This is a small pilot study focused on building models, not treating patients. The models may not perfectly mimic real tumors, and results may not translate to clinical practice.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • Chao Family Comprehensive Cancer Center, University of California, Irvine

    RECRUITING

    Orange, California, 92868, United States

    Contact Email: •••••@•••••

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