Could a simple mist prevent dangerous blood pressure spikes during C-Sections?

NCT ID NCT07164326

Not yet recruiting Disease control Sponsor: Assiut University Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests whether breathing in a sedative called dexmedetomidine before anesthesia can prevent sudden blood pressure rises during emergency C-sections in women with severe preeclampsia. One hundred participants will be randomly assigned to receive either the drug or a placebo mist. The main goal is to see if it keeps blood pressure stable during intubation, with additional checks on eye nerve swelling and throat discomfort.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Dexmedetomidine (a sedative drug given as a mist to breathe in)
What this could lead to: If it works, this could offer a safer way to manage blood pressure spikes during emergency C-sections in women with severe preeclampsia.
What could go wrong: This is a small, early-stage trial (100 people) that hasn't started yet. The drug may not work better than placebo, and side effects like low blood pressure or slow heart rate are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

preeclampsia severe pre-eclampsia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PRESSOR RESPONSE

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