Promising preeclampsia drug trial halted early – what happened?
NCT ID NCT03008616
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested an experimental drug called AMAG-423 (Digoxin Immune Fab) in pregnant women with severe preeclampsia, a dangerous condition of high blood pressure during pregnancy. The goal was to see if the drug could reduce serious health problems in babies, such as bleeding in the brain or bowel issues, and improve kidney function in mothers. The trial was stopped early after enrolling 58 participants, so results are limited.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Adalbertus Hospital
Gdansk, Pomeranian Voivodeship, 80-462, Poland
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Baylor Scott & White Health
Temple, Texas, 76508, United States
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Children's Hospital Foundation Building
Louisville, Kentucky, 40202, United States
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Detroit Medical Center (DMC)
Detroit, Michigan, 48201, United States
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Louisiana State University Health Sciences Center in New Orleans
New Orleans, Louisiana, 70112, United States
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Medical College of Wisconsin
Milwaukee, Wisconsin, 53226, United States
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Regional Obstetrical Consultants
Chattanooga, Tennessee, 37403, United States
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Sefako Makgatho Health Sciences University
Pretoria, Gauteng, 0204, South Africa
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Texas Children's Hospital/Baylor College of Medicine
Houston, Texas, 77030, United States
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The University of Texas Health Science Center at Houston (UTHSC-H)
Houston, Texas, 77303, United States
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The University of Texas Medical Branch (UTMB)
Galveston, Texas, 77555, United States
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University Hospitals Case Medical Center-Case Western Reserve University (CWRU)
Cleveland, Ohio, 44106, United States
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University Of Mississippi Medical Center
Jackson, Mississippi, 39216, United States
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University of Cincinnati Medical Center
Cincinnati, Ohio, 45219, United States
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University of Kansas Medical Center
Kansas City, Kansas, 66160, United States
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University of Maryland
Baltimore, Maryland, 21201, United States
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University of South Alabama
Mobile, Alabama, 36604, United States
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University of Virginia School Of Medicine
Charlottesville, Virginia, 29208, United States