Could a daily baby aspirin help moms recover from severe preeclampsia?

NCT ID NCT03667326

Recruiting now Disease control Sponsor: Columbia University Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing whether taking a low-dose aspirin (81 mg) daily for three weeks after giving birth can improve blood vessel function in women who had severe preeclampsia. About 100 women will be randomly assigned to receive either aspirin or a placebo. The main goal is to see if aspirin helps the lining of blood vessels work better, which might lower the risk of long-term heart problems.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: low-dose aspirin (81 mg tablet)
What this could lead to: If it works, this could point toward a simple, low-cost way to help blood vessels recover faster after severe preeclampsia, potentially reducing long-term heart risks.
What could go wrong: This is a small, early-phase trial testing a short-term effect on a surrogate marker (blood vessel function), not on hard outcomes like heart disease. It may not show a meaningful benefit or change clinical practice.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

preeclampsia severe pre-eclampsia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PREECLAMPSIA POSTPARTUM

Contacts and locations

Locations

Columbia University Irving Medical Center
RECRUITING

New York, New York, 10032, United States

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