Sedative showdown: dexmedetomidine vs ketamine for varicocele surgery

NCT ID NCT07214701

Not yet recruiting Symptom relief Sponsor: Assiut University Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two sedative drugs, dexmedetomidine and ketamine, given before spinal anesthesia for varicocele surgery. The goal is to see which one provides better sedation and fewer side effects. The trial will involve 58 men aged 18 to 40.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

dexmedetomidine and ketamine

What this could lead to

If this trial succeeds, it could help doctors choose the better sedative for varicocelectomy, improving patient comfort and safety during the procedure.

What could go wrong

This is a small, early-phase trial with only 58 participants, so results may not apply to everyone. Both drugs have side effects like low blood pressure or agitation.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

varicocele

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

VARICOCELECTOMY