Gut protein zonulin: a hidden clue to male infertility?
NCT ID NCT07748104
First seen Aug 05, 2026 · Last updated Aug 06, 2026 · Updated 1 time
Summary
This study looks at whether levels of a protein called zonulin, found in blood and semen, differ between infertile men with and without varicocele (enlarged veins in the scrotum). Researchers will measure zonulin in 119 men and compare it with standard semen quality measures like sperm count and movement. The goal is to see if zonulin could serve as a marker for infertility in men with varicocele.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If a link is found, zonulin might become a marker to help diagnose or understand male infertility related to varicocele.
- What could go wrong
- This is an observational study, so it cannot prove cause and effect. The findings may not apply to all men with varicocele.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Gazi State Hospital
Samsun, İlkadım, Turkey (Türkiye)
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Other studies related to the condition(s) this trial covers.
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