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Sperm protein could be key to unlocking male infertility

NCT ID NCT07684339

Recruiting now Knowledge-focused Sponsor: Fakih IVF Fertility Center Source: ClinicalTrials.gov ↗

First seen Jul 06, 2026 · Last updated Jul 07, 2026 · Updated 1 time

Summary

This study looks at whether levels of a sperm protein called PLCZeta are linked to semen quality and fertility outcomes. Researchers will measure PLCZeta in sperm samples from couples undergoing IVF or routine semen analysis. The goal is to see if low or abnormal PLCZeta predicts lower pregnancy or live birth rates. This is an observational study, so no treatment is given.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If PLCZeta proves to be a reliable marker, it could help diagnose male infertility and guide treatment choices in IVF.
What could go wrong
This is an observational study, not a treatment trial. It may not find a clear link, and results may not apply to all fertility cases.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

male infertility

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MALE INFERTILITY MALE SUBFERTILITY

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Fakih IVF

    RECRUITING

    Abu Dhabi, United Arab Emirates

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Khalifa University

    ACTIVE_NOT_RECRUITING

    Abu Dhabi, United Arab Emirates

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