Can a microwave probe vaporize breast lumps without surgery?
NCT ID NCT07719634
First seen Jul 22, 2026 · Last updated Jul 23, 2026 · Updated 1 time
Summary
This trial investigates whether ultrasound-guided microwave ablation (MWA) can safely shrink breast fibroadenomas—noncancerous lumps—and eventually make them disappear. Forty-five women with symptomatic or bothersome fibroadenomas will receive the outpatient procedure, which uses a thin antenna to heat and destroy the tissue. The study will measure how much the lump shrinks over 12 months and track any side effects, aiming to see if MWA can be a scar-free alternative to surgical removal.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- microwave ablation (a device that uses heat to destroy tissue)
- What this could lead to
- If effective, microwave ablation could offer a minimally invasive alternative to surgery for removing breast fibroadenomas, with less scarring and faster recovery.
- What could go wrong
- This is a small, early-phase trial with only 45 participants, so results may not apply broadly. Risks include skin burns, infection, or incomplete shrinkage of the fibroadenoma.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 45 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Aug 2026
An estimate. Start dates often move.
- Expected to finish
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Aug 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion criteria: * Female participants ≥ 18 years * Diagnosed with fibroadenoma by clinical and ultrasonographic signs, core needle biopsy done only if atypical fibroadenoma. * Lesion(s) measurable by ultrasound (e.g., diameter 0.7 - 3.0 cm),distance from breast lesion to the skin and pectoralis muscle exceeding 10 mm and the lesion away from nipple areola area . * Symptomatic lesion or patient preference for minimally invasive treatment Exclusion criteria: * Malignancy or high suspicion of malignancy, BIRADs 4 or more/if pathological proved. * Active infection. * Coagulopathy or contraindications to ablation. * Distance from breast lesion to the skin and pectoralis muscle less than 10 mm and the lesion near nipple areola area .
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
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