Can a simple drug stop shivering during surgery? new trial aims to find out
NCT ID NCT07300826
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests two common sedatives, dexmedetomidine and midazolam, to see which better prevents shivering in trauma patients having lower leg surgery under spinal anesthesia. Shivering affects up to 60% of these patients and can cause discomfort and complications. The trial will enroll 100 adults and monitor shivering during and after surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Dexmedetomidine and midazolam
What this could lead to
If this trial succeeds, it could show that one of these drugs is better at preventing shivering during surgery, improving patient comfort and safety.
What could go wrong
This is a small, early-phase trial with only 100 participants, so results may not apply to all patients. Shivering prevention is a secondary benefit, not a cure.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.