Can a simple drug stop shivering during surgery? new trial aims to find out
NCT ID NCT07300826
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests two common sedatives, dexmedetomidine and midazolam, to see which better prevents shivering in trauma patients having lower leg surgery under spinal anesthesia. Shivering affects up to 60% of these patients and can cause discomfort and complications. The trial will enroll 100 adults and monitor shivering during and after surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Dexmedetomidine and midazolam
- What this could lead to
- If this trial succeeds, it could show that one of these drugs is better at preventing shivering during surgery, improving patient comfort and safety.
- What could go wrong
- This is a small, early-phase trial with only 100 participants, so results may not apply to all patients. Shivering prevention is a secondary benefit, not a cure.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.