New 'Woundsome' technique aims to save legs from amputation

NCT ID NCT07488637

Not yet recruiting Disease control Sponsor: Assiut University Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a procedure called woundsome revascularization in 50 people with chronic limb-threatening ischemia (CLTI), the most severe form of peripheral artery disease. Doctors use balloon angioplasty to open blocked arteries that supply blood directly to the wound area. The goal is to see if this targeted approach can save more limbs from amputation.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Percutaneous Transluminal Angioplasty (balloon angioplasty)
What this could lead to: If successful, this could improve limb salvage rates for people with severe leg artery disease, reducing the need for amputation.
What could go wrong: This is a small, early-stage study with only 50 participants, so results may not apply to everyone. The procedure carries risks like bleeding or vessel damage.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Chronic Limb-Threatening Ischemia limb ischemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHRONIC LIMB-THREATENING ISCHEMIA

Contacts and locations

Locations

Vascular and Endovascular surgery department Assiut university

Asyut, Asyut Governorate, 71511, Egypt

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