Can a sound wave camera inside arteries save more legs?

NCT ID NCT07731997

First seen Jul 28, 2026 · Last updated Jul 29, 2026 · Updated 1 time

Summary

This study compares two ways to guide a minimally invasive procedure that opens blocked arteries below the knee in people with chronic limb-threatening ischemia, a severe form of peripheral artery disease. One group receives standard X-ray guidance (angiography) alone; the other also gets intravascular ultrasound, which uses a tiny camera on a catheter to give a detailed inside view of the artery. The main question is whether adding ultrasound helps keep the artery open longer and reduces the need for repeat procedures or amputation.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Intravascular ultrasound (IVUS) imaging added to standard X-ray angiography during endovascular therapy
What this could lead to
If IVUS proves better, it could become the new standard for guiding leg-artery procedures, potentially reducing repeat blockages and amputations.
What could go wrong
This is a single-center trial with 212 participants, so results may not apply broadly. IVUS adds cost and procedure time, and it is not yet clear whether the extra detail translates into better outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for CHRONIC LIMB-THREATENING ISCHEMIA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Chronic Limb-Threatening Ischemia limb ischemia peripheral arterial disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Chi Mei Medical Center

    Tainan, 710, Taiwan

  • Linkou Chang Gung Memorial Hospital

    Taoyuan, 333, Taiwan

  • National Taiwan University Hospital

    Taipei, 100, Taiwan

  • Shin Kong Wu Ho-Su Memorial Hospital

    Taipei, 111, Taiwan

More trials for these conditions

Other studies related to the condition(s) this trial covers.