New MRI techniques could sharpen diagnosis of optic nerve inflammation

NCT ID NCT07748819

Not yet recruiting Diagnosis Sponsor: Assiut University Source: ClinicalTrials.gov ↗

First seen Aug 06, 2026 · Last updated Aug 07, 2026 · Updated 1 time

Summary

This study tests whether two advanced MRI techniques, called Double Inversion Recovery (DIR) and Diffusion Tensor Imaging (DTI), can improve the assessment of optic neuritis—inflammation of the optic nerve that can affect vision. Researchers will compare MRI measurements of the affected nerve between people with optic neuritis and healthy volunteers, and see how these measurements relate to visual outcomes. The goal is to determine if these imaging methods can more accurately detect and characterize optic nerve damage.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: MRI scans using Double Inversion Recovery (DIR) and Diffusion Tensor Imaging (DTI) sequences
What this could lead to: If successful, this could lead to more accurate MRI-based assessment of optic neuritis, helping to predict visual outcomes and guide treatment decisions.
What could go wrong: This is a relatively small, early-stage study. The imaging techniques may not prove to be more useful than standard MRI, and results may not apply to all patients with optic neuritis.

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Conditions

The condition(s) this trial relates to.

optic nerve disorder optic neuritis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OPTIC NERVE DISEASE

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