New drug aims to save sight in optic neuritis patients
NCT ID NCT07623668
First seen Jun 26, 2026 · Last updated Aug 14, 2026 · Updated 6 times
Summary
This Phase 3 trial tests whether privosegtor, a neuroprotective drug, can improve vision recovery in people having their first episode of optic neuritis. About 210 adults aged 18 to 50 will receive either privosegtor or a placebo, both alongside standard steroid treatment. The main goal is to see if more patients gain at least 15 letters on a vision chart after treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- privosegtor (OCS-05)
- What this could lead to
- If it works, this could lead to a new treatment that helps people with optic neuritis recover more vision than standard care alone.
- What could go wrong
- This is a Phase 3 trial, but it is still experimental. The drug may not improve vision more than placebo, and side effects are possible.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Email: •••••@•••••
Locations
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Kahana Oculoplastic and Orbital Surgery
RECRUITINGLivonia, Michigan, 48152, United States
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Medical University of South Carolina, Storm Eye Institute
RECRUITINGCharleston, South Carolina, 29425, United States
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Neuro-Eye Clinical Trials
RECRUITINGHouston, Texas, 77074, United States
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UT Southwestern Medical Center (Ophthalmology CRU)
RECRUITINGDallas, Texas, 75390, United States
Contact Email: •••••@•••••
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