No opioids? new anesthesia method tested for gallbladder surgery

NCT ID NCT07306910

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether using a combination of lidocaine, dexmedetomidine, and magnesium instead of opioids can control pain and reduce nausea after gallbladder removal. 110 adults having elective laparoscopic cholecystectomy will be randomly assigned to opioid-free or standard opioid anesthesia. The main goal is to see if pain scores are lower with the opioid-free approach.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

opioid-free anesthesia (lidocaine, dexmedetomidine, magnesium)

What this could lead to

If it works, this could offer a safer way to manage pain during gallbladder surgery without using opioids.

What could go wrong

This is a small, early-stage study that hasn't started yet. The approach may not control pain as well as standard care, and side effects from the alternative drugs are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

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