No opioids? new anesthesia method tested for gallbladder surgery

NCT ID NCT07306910

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests whether using a combination of lidocaine, dexmedetomidine, and magnesium instead of opioids can control pain and reduce nausea after gallbladder removal. 110 adults having elective laparoscopic cholecystectomy will be randomly assigned to opioid-free or standard opioid anesthesia. The main goal is to see if pain scores are lower with the opioid-free approach.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
opioid-free anesthesia (lidocaine, dexmedetomidine, magnesium)
What this could lead to
If it works, this could offer a safer way to manage pain during gallbladder surgery without using opioids.
What could go wrong
This is a small, early-stage study that hasn't started yet. The approach may not control pain as well as standard care, and side effects from the alternative drugs are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

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