Elderly surgery study: right ventilator settings may protect the brain

NCT ID NCT07505550

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at how different ventilator pressure levels (PEEP) affect blood flow and brain function in 78 elderly patients having gallbladder surgery. Patients were split into three groups, each receiving a different PEEP level. The goal was to see which level best maintains blood circulation and prevents mental decline after surgery. The study is complete and aims to guide safer anesthesia care for older adults.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

different levels of positive end-expiratory pressure (PEEP) during mechanical ventilation

What this could lead to

If successful, this study could help doctors choose the best ventilator settings to protect brain function and blood flow in elderly patients during surgery.

What could go wrong

This is a small, completed study with only 78 patients, so results may not apply to all elderly patients or surgeries. It does not test a new drug or treatment.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Ankara Bilkent City Hospital

    Ankara, Çankaya, 06800, Turkey (Türkiye)