Can skipping opioids speed up recovery from thyroid surgery?

NCT ID NCT05577962

Recruiting now Symptom relief Sponsor: Beijing Friendship Hospital Source: ClinicalTrials.gov ↗

First seen Aug 05, 2026 · Last updated Aug 06, 2026 · Updated 1 time

Summary

This trial tests whether an opioid-free anesthesia approach can improve early recovery quality after thyroidectomy compared to traditional balanced anesthesia. Adults undergoing elective thyroid surgery will be randomly assigned to receive either the opioid-free protocol or standard care. The main goal is to compare recovery scores, pain levels, and complication rates in the first days after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Opioid-free anesthesia protocol using dexamethasone, flurbiprofen axetil, dexmedetomidine, lidocaine, esketamine, propofol, and rocuronium
What this could lead to: If successful, this approach could offer a safer, more comfortable recovery from thyroid surgery without the side effects of opioids.
What could go wrong: This is a single-center trial with 160 participants, so results may not apply broadly. The opioid-free regimen may not control pain as effectively for everyone, and there are risks from the alternative drugs used.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OPIOID-FREE ANESTHESIA

Contacts and locations

Locations

Beijing Friendship Hospital, Capital Medical University
RECRUITING

Beijing, Beijing Municipality, 100050, China

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