Beijing Friendship Hospital

This study tests a new surgical method (TLSA) that avoids cutting a key nerve during hiatal hernia repair, compared to the standard approach. About 143 adults with a hiatal hernia and stubborn acid reflux will be randomly assigned to one of the two surgeries. The goal is to see i…

This study tests a drug called golidocitinib for people with hemophagocytic lymphohistiocytosis (HLH), a rare condition where the immune system attacks the body. About 28 adults aged 14 to 70 with new or returning HLH will take the drug alone. The goal is to see if it can normali…

This study tests whether combining two drugs, golidocitinib and selinexor, can control chronic active Epstein-Barr virus disease (CAEBVD). About 28 adults with active symptoms will receive the treatment. The goal is to reduce virus levels and improve disease activity.

This study tests whether a combination of four drugs (adebrelimab, apatinib, oxaliplatin, and tigio) can shrink advanced stomach or gastroesophageal junction cancer enough to allow surgical removal. About 49 adults with cancer that cannot currently be removed will receive up to 8…

This study is testing a new bioartificial liver device (CiPS-BAL) in 12 people with liver failure or small-for-size syndrome. The main goal is to see if the device is safe and tolerable, while also checking how it affects liver function and overall health. Participants will recei…

This study tests whether adding the immunotherapy drug tislelizumab to standard chemoradiation can improve outcomes for people with locally advanced rectal cancer. About 375 adults will receive either chemoradiation alone or combined with tislelizumab before surgery. The goal is …

This study tests a new drug combination (iparomlimab and tuvonralimab, called QL1706) plus chemotherapy in people with advanced stomach or gastroesophageal junction cancer that hasn't been treated yet. The goal is to see if the combination shrinks tumors and is safe. About 32 par…

This study compares two blood thinners—rivaroxaban and warfarin—in people with a kidney condition called idiopathic membranous nephropathy who are at high risk for dangerous blood clots. About 134 participants will take one of the medications for 6 months to see which better prev…

This study tests a new surgery that uses a fluorescent dye to find and remove only the cancer-affected lymph nodes in people with early stomach cancer. The goal is to remove the tumor while keeping as much of the stomach working as possible, improving quality of life. About 312 a…

This study tests whether a smartphone-based rehab program can reduce complications and improve recovery in 186 gastric cancer patients who receive chemotherapy before surgery. Participants follow a tailored exercise, nutrition, and mental health plan from before surgery until fou…

This early-stage study is testing a new medication for Restless Legs Syndrome (RLS), a condition that causes uncomfortable urges to move the legs. About 20 adults with moderate to severe RLS will take the drug twice daily for 12 weeks. Researchers will measure changes in symptom …

This study looks at two types of anesthesia—conscious sedation and general anesthesia—used during painless gastroscopy (a stomach exam) in frail adults aged 65 and older. The goal is to see which method causes fewer heart-related problems like irregular heartbeat or blood pressur…

This study will follow 4,000 people with primary biliary cholangitis (PBC), a chronic autoimmune liver disease, to learn more about their symptoms, treatment responses, and long-term health outcomes. Researchers want to understand why some patients do not respond well to standard…

This study is building a model using patient data (like scans and gut bacteria) to see who responds so well to initial therapy that they might not need surgery. It involves 869 adults with stage II/III rectal cancer. The goal is to help doctors choose the best timing for surgery …

This study will follow 3000 people in China who have liver injury caused by medications or herbs. Researchers will track their health to find patterns and risk factors that affect recovery. The goal is to create a tool that helps doctors predict who will get better and who might …

This study is testing a personalized blood test that looks for cancer DNA to predict how well pre-surgery treatment works for people with locally advanced rectal cancer. Researchers will collect blood and tissue samples from 60 participants over time to build a model that forecas…

This study looks at how chronic kidney disease affects the eyes, brain, and kidneys together. Researchers will use MRI scans and eye imaging to see if changes in the brain and retina are linked to memory problems and kidney function. About 1,500 adults with CKD will take part, bu…