No-Opioid anesthesia beats standard for gallbladder surgery recovery
NCT ID NCT07307625
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether avoiding opioids during gallbladder surgery could improve recovery. 101 patients received either opioid-free anesthesia (using lidocaine and dexmedetomidine) or standard opioid anesthesia. The opioid-free group had less pain after surgery, needed fewer painkillers, and had less nausea and vomiting. They also woke up faster and had better early recovery scores.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- lidocaine and dexmedetomidine
- What this could lead to
- If confirmed, this approach could offer a safer, more comfortable anesthesia option for gallbladder surgery, reducing opioid use and side effects like nausea.
- What could go wrong
- This was a small, single-center trial with only 101 patients. Larger, more diverse studies are needed to confirm these results and ensure safety for broader use.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for GENERAL ANESTHESIA are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
SBÜ Kartal Dr. Lütfi Kırdar City Hospital
Istanbul, Turkey (Türkiye)
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a simple anesthetic choice prevent Post-Surgery vomiting?
- Which nerve block eases gallbladder surgery pain better?
- Can a targeted nerve block cut opioid use in High-Risk C-Sections?
- Can a new sedative make anesthesia safer for seniors?
- Can skipping opioids speed up recovery from thyroid surgery?
- Can a lighter sedative dose keep patients calm after nasal surgery?