No-Opioid anesthesia beats opioids for gallbladder surgery recovery

NCT ID NCT07307625

First seen Jan 05, 2026 · Last updated May 13, 2026 · Updated 17 times

Summary

This study tested whether avoiding opioids during gallbladder surgery could improve recovery. 101 adults having laparoscopic gallbladder removal were randomly assigned to receive either opioid-free anesthesia (using lidocaine and dexmedetomidine) or standard opioid-based anesthesia. The opioid-free group had less pain after surgery, needed fewer painkillers, and had less nausea and vomiting. The approach appears safe and effective for improving recovery after this common surgery.

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Contacts and locations

Locations

  • SBÜ Kartal Dr. Lütfi Kırdar City Hospital

    Istanbul, Turkey (Türkiye)

Conditions

Explore the condition pages connected to this study.