LAPAROSCOPIC CHOLECYSTECTOMY

This study looks at 64 adults with moderate to severe gallbladder inflammation who had a drainage tube placed. It compares removing the gallbladder early (during the same hospital stay) versus waiting over 6 weeks. The goal is to see which timing leads to fewer complications and …

This study tests if taking ginger before gallbladder surgery can prevent nausea and vomiting afterward. About 102 adults having laparoscopic gallbladder removal will take either ginger or a placebo two hours before surgery. Researchers will track how many people feel sick in the …

This study tests whether a nerve block (erector spinae plane block) combined with low-flow anesthesia can improve recovery and reduce opioid use after laparoscopic gallbladder removal. 72 adults aged 18-65 will be randomly assigned to receive either the nerve block plus low-flow …

This study tests whether injecting a combination of a local anesthetic (ropivacaine) and a steroid (triamcinolone) into the incision site before laparoscopic surgery can reduce pain better than the anesthetic alone. The trial will enroll 150 adults undergoing gallbladder, appendi…

This study tests whether injecting a combination of a numbing drug (ropivacaine) and an anti-inflammatory steroid (diprospan) into the incision site before laparoscopic surgery can reduce pain better than the numbing drug alone. About 150 adults having gallbladder, appendix, or h…

This study tests whether placing a loxoprofen sodium patch on the skin where surgical cuts will be made can reduce pain after laparoscopic surgery. About 134 adults having gallbladder, appendix, or hernia surgery will take part. The goal is to see if this simple step lowers the n…

This study compares two ultrasound-guided nerve blocks—recto-intercostal fascial plane block (RIFPB) and transversus abdominis plane block (TAPB)—for pain control after laparoscopic gallbladder removal. 90 adults undergoing elective surgery will receive one of the two blocks. The…

This study tests whether a specific nerve block, called an external oblique intercostal block, can reduce pain and the need for opioid painkillers after laparoscopic gallbladder removal. Fifty-six adults scheduled for this surgery will be randomly assigned to receive either the n…

This study compares two types of nerve blocks—erector spinae plane block and modified thoracoabdominal nerve block—for pain control after laparoscopic gallbladder removal. Fifty adults aged 30-65 will receive one of the two blocks with bupivacaine. Researchers will measure how lo…

This study compares two types of nerve blocks (paravertebral block and external oblique intercostal block) to standard pain medicine for people having gallbladder removal surgery. About 147 adults will be randomly assigned to one of three groups to see which approach reduces pain…

This study looks at 70 adults having gallbladder removal surgery to see if one type of low-flow anesthesia (sevoflurane or desflurane) causes less sore throat afterward. Participants will be randomly assigned to one of the two anesthetics. The goal is to find which option leads t…

This study looks at whether giving a numbing injection to the belly muscles before or after gallbladder surgery helps reduce pain and the need for strong painkillers. About 96 adults having their gallbladder removed will be randomly assigned to get the injection either before the…

This study tests whether an artificial intelligence tool can help surgeons perform safer gallbladder removal surgery. About 70 patients having laparoscopic cholecystectomy will be randomly assigned to receive AI guidance or standard care. The goal is to see if AI helps surgeons a…

This study compares two ultrasound-guided nerve blocks—M-TAPA and quadratus lumborum block—for pain after laparoscopic gallbladder removal. Fifty-two adults undergoing surgery will receive one of the two blocks, and researchers will measure how long it takes before they need addi…

This study tests whether labetalol or lignocaine (lidocaine) is better at preventing sudden rises in heart rate and blood pressure when a breathing tube is inserted for gallbladder surgery. 116 adults having elective laparoscopic gallbladder removal will receive one of the two dr…

This study tests whether a set of tools—like doctor education, decision aids, and financial incentives—can reduce unnecessary medical tests before low-risk surgeries such as breast lump removal, gallbladder removal, and hernia repair. Sixteen hospitals in Michigan will use these …

This study looks at whether giving less IV fluid after gallbladder removal is as safe and effective as giving more. About 380 adults having planned laparoscopic gallbladder surgery will be randomly assigned to receive either liberal or restricted fluids for 6 hours after the oper…

This study looks at two different nerve blocks used to manage pain after gallbladder removal surgery. Researchers will map where on the skin each block causes numbness and see which one covers the surgical cuts better. The goal is to learn more about these blocks to improve pain …

This study compares two widely used inhaled anesthetics, isoflurane and sevoflurane, to see which one causes less oxidative stress (a type of cell damage) in patients having gallbladder removal surgery. Researchers will measure stress markers in the blood of 80 healthy adults. Th…